Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834630 | 0.85 | MAPT (0.33) | PGRGAAHTTKMT2AMAPT | |
| SCHEMBL9834766 | 0.84 | KMT2A (0.48) | PGRGAAHTTKMT2A | |
| SCHEMBL9833658 | 0.79 | FABP6 (0.43) | PGRKMT2AMEN1TDP1 | |
| SCHEMBL9835234 | 0.79 | PGR (0.40) | PGRADAMTS5 | |
| SCHEMBL9834590 | 0.79 | PGR (0.40) | PGRATMADAMTS5 | |
| SCHEMBL9835004 | 0.77 | HPGD (0.40) | PGRHTTKMT2AMAPTMEN1 | |
| SCHEMBL9836082 | 0.77 | KDM4E (0.43) | PGRHTTKMT2AMEN1ATM | |
| SCHEMBL9834606 | 0.76 | KDM4E (0.45) | PGRHTTMAPT | |
| SCHEMBL9834640 | 0.76 | CHRNB2 (0.39) | MAPTTP53TDP1ADAMTS5 | |
| SCHEMBL10374413 | 0.75 | PGR (0.47) | PGRGAAHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214592-B1 | PYRROLOBENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE PRODUCTS | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4730003-A | Tricyclic compounds for treating heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-03-08 | — | — | US | disclosed |
| EP-0214592-A2 | Pyrrolobenzimidazoles, process for their preparation and medicaments containing these products | Roche Diagnostics GmbH (DE) | 1987-03-18 | — | — | EP | disclosed |