Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | AHCY | P23526 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835465 | 0.88 | BCHE (0.49) | BCHEACHEMEN1KMT2ATSHR | |
| SCHEMBL9837010 | 0.85 | HPGD (0.41) | BCHEACHEFAAHSMN1; SMN2MEN1 | |
| SCHEMBL9836932 | 0.82 | TSHR (0.43) | BCHEACHEALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9836532 | 0.81 | PDE3B (0.35) | SMN1; SMN2HTR4 | |
| SCHEMBL9835522 | 0.80 | HPGD (0.45) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL9835976 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL9836412 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2HPGDGAA | |
| SCHEMBL9834628 | 0.78 | MAPT (0.43) | ALDH1A1SMN1; SMN2HPGDPOLBGAA | |
| SCHEMBL9837594 | 0.78 | PDE3B (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL9835111 | 0.77 | ALDH1A1 (0.53) | BCHEACHEALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238357-B1 | 1,2,4-TRIAZINONE DERIVATIVES, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-29 | — | — | EP | claimed |
| US-4898862-A | 1,2,4-triazinone derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1990-02-06 | — | — | US | claimed |
| EP-0238357-A2 | 1,2,4-Triazinone derivatives, their preparation and use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | claimed |
| US-4898862-A | 1,2,4-triazinone derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0238357-A2 | 1,2,4-Triazinone derivatives, their preparation and use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |