Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835465 | 0.86 | BCHE (0.49) | KMT2AMEN1BCHEACHELMNA | |
| SCHEMBL9833975 | 0.85 | BCHE (0.39) | HPGDKMT2AMEN1BCHEACHE | |
| SCHEMBL9836932 | 0.80 | TSHR (0.43) | HPGDUSP2KDM4EBCHEACHE | |
| SCHEMBL9835522 | 0.78 | HPGD (0.45) | HPGDUSP2KDM4EKMT2AMEN1 | |
| SCHEMBL10768462 | 0.77 | HPGD (0.41) | HPGDUSP2KDM4EKMT2AMEN1 | |
| SCHEMBL9835976 | 0.77 | SMN1; SMN2 (0.47) | HPGDUSP2KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9836412 | 0.77 | ALDH1A1 (0.51) | HPGDSMN1; SMN2LMNA | |
| SCHEMBL9834628 | 0.76 | MAPT (0.43) | HPGDKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9837594 | 0.76 | PDE3B (0.41) | HPGDKDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9836049 | 0.76 | MEN1 (0.50) | HPGDKMT2AMEN1SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238357-B1 | 1,2,4-TRIAZINONE DERIVATIVES, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-29 | — | — | EP | claimed |
| US-4898862-A | 1,2,4-triazinone derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1990-02-06 | — | — | US | claimed |
| EP-0238357-A2 | 1,2,4-Triazinone derivatives, their preparation and use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | claimed |
| US-4898862-A | 1,2,4-triazinone derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0238357-A2 | 1,2,4-Triazinone derivatives, their preparation and use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |