Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10043038 | 0.92 | BCHE (0.51) | SLC6A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9835834 | 0.89 | GAA (0.61) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL12748169 | 0.79 | SIGMAR1 (0.53) | SLC6A4SLC6A3 | |
| SCHEMBL9835308 | 0.79 | SLC6A1 (0.63) | SLC6A1 | |
| SCHEMBL9714856 | 0.78 | CYP3A4 (0.59) | SLC6A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9834615 | 0.78 | SLC6A1 (0.59) | SLC6A1 | |
| SCHEMBL8647649 | 0.77 | LMNA (0.83) | LMNANPSR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8642037 | 0.77 | LMNA (0.78) | LMNANPSR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8645362 | 0.76 | LMNA (0.81) | LMNANPSR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6082540 | 0.75 | GAA (0.78) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221572-B1 | N-SUBSTITUTED 3-PIPERIDINE-OR 3-PYRIDINE-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | WARNER-LAMBERT COMPANY (US) | 1991-09-25 | — | — | EP | claimed |