Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714856 | 0.90 | CYP3A4 (0.59) | CYP3A4SLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL9833980 | 0.89 | LMNA (0.54) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9836380 | 0.83 | CYP3A4 (0.57) | CYP3A4SLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL10043038 | 0.81 | BCHE (0.51) | SLC6A2SLC6A4SLC6A3KMT2ABCHE | |
| SCHEMBL9835308 | 0.79 | SLC6A1 (0.63) | — | |
| SCHEMBL9837074 | 0.78 | SLC6A1 (0.51) | — | |
| SCHEMBL9836368 | 0.77 | SLC6A1 (0.53) | CYP3A4SLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL4840777 | 0.76 | GAA (1.00) | GAAKDM2BGLAHSD17B10KMT2A | |
| SCHEMBL9834615 | 0.76 | SLC6A1 (0.59) | CYP3A4CYP1A2KDM2BKMT2ASLC6A12 | |
| SCHEMBL7925390 | 0.75 | SLC6A12 (0.57) | SLC6A12SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221572-B1 | N-SUBSTITUTED 3-PIPERIDINE-OR 3-PYRIDINE-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | WARNER-LAMBERT COMPANY (US) | 1991-09-25 | — | — | EP | claimed |