SCHEMBL9834244

SCHEMBL9834244

CC=C(C)C(OC(=O)Nc1ccc(F)cc1)C(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
MEN1 O00255 3/20 0.42
MAPT P10636 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42
CYP2C19 P33261 1/20 0.42
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 1/20 0.41
KDM4E B2RXH2 1/20 0.41
KLK7 P49862 1/20 0.40
FAAH O00519 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835939 0.86 MAPT (0.51) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL9835863 0.86 SMN1; SMN2 (0.44) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL9835566 0.84 ALDH1A1 (0.44) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL9836705 0.80 IDO1 (0.41) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL9836991 0.78 MAPT (0.46) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL9837673 0.74 RORC (0.48) NPC1RAB9ASMN1; SMN2MAPTHTT
SCHEMBL27309652 0.74 MEN1 (0.43) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL17904708 0.74 NPC1 (0.67) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL2097993 0.74 RAB9A (0.50) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL2095091 0.73 SMN1; SMN2 (0.67) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1027069-C Process for producing oxazolidinedione derivative SAGAMI CHEM RES (JP) 1994-12-21 CN disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed