Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832805 | 0.91 | OPRM1 (0.70) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| Maleic Acid SCHEMBL9832430 | 0.85 | ALDH1A1 (0.74) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| Fumaric Acid SCHEMBL9832433 | 0.85 | ALDH1A1 (0.74) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| SCHEMBL9834283 | 0.84 | OPRM1 (0.58) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| SCHEMBL9833668 | 0.80 | OPRM1 (0.57) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| SCHEMBL10560140 | 0.76 | L3MBTL1 (0.51) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| SCHEMBL9834231 | 0.76 | L3MBTL1 (0.53) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| SCHEMBL14317655 | 0.75 | OPRM1 (0.83) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| Trimebutine SCHEMBL25705 | 0.75 | OPRM1 (1.00) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| Trimebutine SCHEMBL14273976 | 0.75 | OPRM1 (1.00) | OPRM1OPRD1NR1I2CHRM2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297782-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-22 | — | — | EP | disclosed |
| US-4857543-A | TREATMENT OF GASTROINTESTINAL DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |