SCHEMBL9834281

SCHEMBL9834281

CC(C)=C1OC(=O)N(c2cc(O)c(Cl)cc2Cl)C1=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MCL1 Q07820 1/20 0.31
HSP90AA1 P07900 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7932830 0.87 PPOX (0.32) HPGD
SCHEMBL9837248 0.86 HPGD (0.30) HPGDTSHRHSD17B10
SCHEMBL9836995 0.79 BCL2A1 (0.42) HPGD
SCHEMBL9835969 0.79 PPOX (0.45) HPGDTSHRHSD17B10
SCHEMBL9834577 0.78 CUL4A (0.45) HSP90AA1
SCHEMBL9835991 0.73 TSHR (0.39) HPGDTSHRHSD17B10
SCHEMBL9814246 0.73 HPGD (0.35) HPGDTSHRHSD17B10HSP90AA1
SCHEMBL9655656 0.72 HPGD (0.34) HPGDTSHRHSD17B10HSP90AA1
SCHEMBL10487767 0.68
SCHEMBL9577463 0.68 PPOX (0.47) HPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed