Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943141 | 0.71 | GAA (0.46) | MEN1KMT2AALDH1A1GAAHSD17B10 | |
| SCHEMBL8556056 | 0.71 | GAA (0.46) | MEN1KMT2AALDH1A1GAABRPF1 | |
| SCHEMBL155144 | 0.68 | GAA (0.48) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7427944 | 0.68 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1GAABRPF1 | |
| SCHEMBL9834304 | 0.68 | GAA (0.40) | MEN1KMT2AALDH1A1GAABRPF1 | |
| SCHEMBL2828423 | 0.67 | GAA (0.52) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8805855 | 0.64 | BRPF1 (0.47) | MEN1KMT2AGAABRPF1HSD17B10 | |
| SCHEMBL6630243 | 0.63 | BRD4 (0.47) | MEN1KMT2AALDH1A1GAAHSD17B10 | |
| SCHEMBL10648460 | 0.63 | NOX1 (0.46) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4510651 | 0.63 | GAA (0.52) | MEN1KMT2AALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |