Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008266 | 0.83 | ESRRA (0.59) | ESRRAALDH1A1ALOX15NR1I2LMNA | |
| SCHEMBL7204289 | 0.82 | ESRRA (0.72) | ESRRAALDH1A1ALOX15NR1I2LMNA | |
| SCHEMBL3126079 | 0.81 | CA2 (0.53) | ALDH1A1ALOX15LMNACYP2C9TYR | |
| SCHEMBL8632740 | 0.74 | ESRRA (0.61) | ESRRAALDH1A1ALOX15NR1I2LMNA | |
| SCHEMBL12323552 | 0.73 | ESRRA (0.65) | ESRRAALDH1A1ALOX15NR1I2LMNA | |
| SCHEMBL6142004 | 0.73 | ALDH1A1 (0.73) | ESRRAALDH1A1ALOX15NR1I2LMNA | |
| SCHEMBL29362042 | 0.73 | ALDH1A1 (0.73) | ESRRAALDH1A1ALOX15NR1I2LMNA | |
| SCHEMBL35535 | 0.73 | ALDH1A1 (0.73) | ESRRAALDH1A1ALOX15NR1I2LMNA | |
| SCHEMBL5083160 | 0.73 | ALDH1A1 (0.56) | ESRRAALDH1A1ALOX15NR1I2LMNA | |
| SCHEMBL20548778 | 0.72 | ALDH1A1 (0.71) | ESRRAALDH1A1ALOX15NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217149-B1 | POLY(2,2,6,6-TETRAMETHYLPIPERIDYLAMINOSPIROGLYCOLETHER-1,3,5-TRIAZINES) | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1991-01-30 | — | — | EP | disclosed |