Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834712 | 0.80 | PNMT (0.42) | NPC1RAB9AALDH1A1KDM4EMAPK1 | |
| SCHEMBL9836665 | 0.77 | KDM4E (0.42) | NPC1RAB9AALDH1A1KDM4EMAPK1 | |
| SCHEMBL9836560 | 0.76 | DHODH (0.34) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9835131 | 0.74 | TSHR (0.41) | NPC1RAB9AALDH1A1KDM4EMAPK1 | |
| SCHEMBL9722742 | 0.73 | CISD2 (0.46) | NPC1RAB9AALDH1A1KDM4EMAPK1 | |
| SCHEMBL9836524 | 0.72 | TBXAS1 (0.43) | NPC1RAB9AKDM4EMAPK1HPGD | |
| SCHEMBL9836663 | 0.71 | KDM4E (0.36) | NPC1RAB9AALDH1A1KDM4EMAPK1 | |
| SCHEMBL9835986 | 0.70 | TBXAS1 (0.46) | NPC1RAB9AKDM4EMAPK1HPGD | |
| SCHEMBL4176316 | 0.69 | KDM4E (0.44) | NPC1RAB9AALDH1A1KDM4EMAPK1 | |
| SCHEMBL9834823 | 0.68 | TBXAS1 (0.40) | NPC1RAB9AALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |