Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822090 | 0.76 | BRD4 (0.43) | BRD4XDHBACE1CTSDNOTUM | |
| SCHEMBL5868948 | 0.71 | HCAR3 (0.42) | BRD4XDHBACE1CTSDNOTUM | |
| SCHEMBL9198201 | 0.71 | XDH (0.45) | TSHRMAPK1BRD4XDHNOTUM | |
| SCHEMBL6996080 | 0.71 | KIF11 (0.44) | PTGS1PTGS2KIF11 | |
| SCHEMBL10850893 | 0.70 | BRD4 (0.43) | TSHRMAPK1BRD4XDHNOTUM | |
| SCHEMBL6997650 | 0.70 | PTGS2 (0.38) | BRD4BACE1CTSDNOTUMPGR | |
| SCHEMBL10849821 | 0.70 | XDH (0.47) | TSHRMAPK1BRD4XDHNOTUM | |
| SCHEMBL10822086 | 0.69 | BRD4 (0.40) | BRD4XDHNOTUMIKBKBPGR | |
| SCHEMBL27564930 | 0.69 | HCAR3 (0.41) | BRD4XDHNOTUMIKBKBPGR | |
| SCHEMBL3789224 | 0.69 | TSHR (0.76) | TSHRMAPK1BRD4XDHNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3120265-A | — | — | None | — | — | JP | disclosed |
| JP-H03120265-A | 5H-FURAN-2-ONE DERIVATIVE | BAYER AG | 1991-05-22 | — | — | JP | disclosed |