SCHEMBL9834890

SCHEMBL9834890

CCCCC(CC)C[n+]1ccc(N(CCCC)CCCC)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 6/20 0.35
CYP3A4 P08684 4/20 0.35
LMNA P02545 2/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
KDM4E B2RXH2 2/20 0.34
HTT P42858 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL9328651 0.98 CHRM2 (0.42) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL6687261 0.98 CHRM2 (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
Bromide SCHEMBL9330064 0.93 KMT2A (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
Hydrochloric Acid SCHEMBL9330763 0.93 MEN1 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL3447497 0.84 ALDH1A1 (0.48) MEN1TP53CYP1A2CYP2D6MAPT
Hydrochloric Acid SCHEMBL3446376 0.83 LMNA (0.47) MAPTALDH1A1CYP3A4LMNAHSD17B10
Bromide SCHEMBL5683015 0.83 CHKA (0.50) ALDH1A1CYP3A4LMNAHSD17B10HTT
Iodide SCHEMBL7861647 0.83 LMNA (0.47) MEN1TP53CYP1A2CYP2D6MAPT
SCHEMBL13061797 0.82 MEN1 (0.52) MEN1TP53CYP1A2CYP2D6MAPT
Bromide SCHEMBL6795666 0.82 CHKA (0.49) ALDH1A1CYP3A4LMNAHSD17B10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0253837-B1 CATALYTIC METHOD FOR PRODUCING FLUOROAROMATIC COMPOUNDS USING BRANCHED ALKYL PYRIDINIUM SALTS MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) 1991-10-09 EP claimed