Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 5/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837503 | 0.86 | TBXAS1 (0.46) | TBXAS1PDE3BPDE3A | |
| SCHEMBL9835838 | 0.76 | KDM4E (0.35) | TBXAS1MAPT | |
| SCHEMBL9836779 | 0.75 | TBXAS1 (0.76) | TBXAS1 | |
| SCHEMBL9835177 | 0.74 | TBXAS1 (0.53) | TBXAS1 | |
| SCHEMBL9835184 | 0.74 | TBXAS1 (0.61) | TBXAS1MAPT | |
| SCHEMBL9836059 | 0.70 | TBXAS1 (0.58) | TBXAS1PDE3BPDE3AMAPTCYP11B1 | |
| SCHEMBL9869742 | 0.68 | TBXAS1 (0.36) | TBXAS1 | |
| SCHEMBL10551166 | 0.68 | TBXAS1 (0.36) | TBXAS1 | |
| SCHEMBL9869737 | 0.68 | TBXAS1 (0.46) | TBXAS1 | |
| SCHEMBL9835663 | 0.68 | TBXAS1 (0.43) | TBXAS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |