SCHEMBL9869737

SCHEMBL9869737

COC(=O)C1=Cc2sc(C(Cn3ccnc3)(OC=S)SC)cc2CC1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 7/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9837312 0.92 TBXAS1 (0.56) TBXAS1
SCHEMBL9834707 0.78 TBXAS1 (0.48) TBXAS1
SCHEMBL9836779 0.76 TBXAS1 (0.76) TBXAS1
SCHEMBL9837207 0.75 TBXAS1 (0.58) TBXAS1
SCHEMBL9835184 0.73 TBXAS1 (0.61) TBXAS1
SCHEMBL9835177 0.73 TBXAS1 (0.53) TBXAS1
SCHEMBL10551166 0.69 TBXAS1 (0.36) TBXAS1
SCHEMBL9869742 0.69 TBXAS1 (0.36) TBXAS1
SCHEMBL9835233 0.68 TBXAS1 (0.43) TBXAS1
SCHEMBL9836683 0.65 TBXAS1 (0.52) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021444-A Anticoagulants SANKYO COMPANY LIMITED (JP) 1991-06-04 US disclosed
US-4847272-A ANTICOAGULANTS SANKYO COMPANY LIMITED (JP) 1989-07-11 US disclosed
EP-0240107-A1 Thianaphthene derivatives, their production and use Sankyo Company Limited (JP) 1987-10-07 EP disclosed