Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837112 | 0.87 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL10552450 | 0.79 | MAOA (0.46) | ALDH1A1KMT2ASMN1; SMN2MAPK1MAP2K1 | |
| SCHEMBL9834910 | 0.79 | KMT2A (0.43) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL9837340 | 0.78 | MAPT (0.37) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL428339 | 0.73 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL14492202 | 0.69 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL21795162 | 0.68 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL1177339 | 0.67 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL2474471 | 0.66 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL10815794 | 0.65 | CYP19A1 (0.66) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261674-B1 | A CYCLOHEXANEDIONE DERIVATIVE AND A PROCESS FOR PRODUCING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1991-06-12 | — | — | EP | claimed |
| US-4863925-A | SUBSTITUTED | NIHON NOHYAKU CO., LTD. (JP) | 1989-09-05 | — | — | US | claimed |
| EP-0261674-A1 | A cyclohexanedione derivative and a process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 1988-03-30 | — | — | EP | claimed |
| EP-0261674-B1 | A CYCLOHEXANEDIONE DERIVATIVE AND A PROCESS FOR PRODUCING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1991-06-12 | — | — | EP | disclosed |
| EP-0261674-A1 | A cyclohexanedione derivative and a process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 1988-03-30 | — | — | EP | disclosed |