Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835316 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL9834910 | 0.74 | KMT2A (0.43) | ALDH1A1KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL9837340 | 0.69 | MAPT (0.37) | ALDH1A1KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL428339 | 0.69 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL10552450 | 0.67 | MAOA (0.46) | ALDH1A1KMT2AMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL1177339 | 0.66 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL14492202 | 0.65 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL21795162 | 0.64 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL1268717 | 0.62 | TSHR (0.69) | ALDH1A1KMT2AMAPK1MAPTGAA | |
| SCHEMBL18117753 | 0.62 | TSHR (0.69) | ALDH1A1KMT2AMAPK1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261674-B1 | A CYCLOHEXANEDIONE DERIVATIVE AND A PROCESS FOR PRODUCING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1991-06-12 | — | — | EP | claimed |
| US-4863925-A | SUBSTITUTED | NIHON NOHYAKU CO., LTD. (JP) | 1989-09-05 | — | — | US | claimed |
| EP-0261674-A1 | A cyclohexanedione derivative and a process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 1988-03-30 | — | — | EP | claimed |