SCHEMBL19923679

SCHEMBL19923679

CC1C(=O)N([Si](c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)N1c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOX P28300 1/20 0.39
LOXL3 P58215 1/20 0.39
LOXL4 Q96JB6 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
MAOA P21397 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HTT P42858 1/20 0.36
GFER P55789 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
GAA P10253 4/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
MAPK1 P28482 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923639 0.85 MAOA (0.41) LOXLOXL3LOXL4LOXL2MAOA
SCHEMBL19923550 0.82 GRM4 (0.47) LOXLOXL3LOXL4LOXL2ALDH1A1
SCHEMBL19923608 0.81 CYP1A2 (0.38) LOXLOXL3LOXL4LOXL2ALDH1A1
SCHEMBL19923424 0.81 TSHR (0.34) LOXLOXL3LOXL4LOXL2MAOA
SCHEMBL19923746 0.81 GRM4 (0.35) LOXLOXL3LOXL4LOXL2MAOA
SCHEMBL19923535 0.81 CYP1A2 (0.40) LOXLOXL3LOXL4LOXL2MAOA
SCHEMBL19923540 0.81 GFER (0.39) ALDH1A1GFERSMN1; SMN2MEN1KMT2A
SCHEMBL19923411 0.80 CYP1A2 (0.42) LOXLOXL3LOXL4LOXL2MAOA
SCHEMBL6713101 0.78 MAOA (0.48) LOXLOXL3LOXL4LOXL2MAOA
SCHEMBL19923602 0.78 SMO (0.37) SMN1; SMN2MEN1KMT2ANPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN LOX 551/4885LOXL3 2027/4885LOXL4 2002/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM LOX 660/4885LOXL3 2218/4885LOXL4 2153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.