Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.47 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.38 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.38 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836636 | 0.80 | PTGS2 (0.47) | MAOATTRKDM5AALDH1A1KDM4E | |
| SCHEMBL10871145 | 0.79 | MGAM (0.42) | MAOATTRALDH1A1KDM4EMAPT | |
| SCHEMBL9834130 | 0.79 | TTR (0.52) | MAOATTRALDH1A1KDM4EMAPT | |
| SCHEMBL9834701 | 0.78 | MAOA (0.49) | MAOATTRKDM5AIKBKBALDH1A1 | |
| SCHEMBL10537230 | 0.72 | TTR (0.44) | MAOATTRKDM5AALDH1A1KDM4E | |
| SCHEMBL9837053 | 0.72 | TTR (0.49) | MAOATTRALDH1A1KDM4EMAPT | |
| SCHEMBL9835296 | 0.72 | TTR (0.52) | MAOATTRALDH1A1KDM4EMAPT | |
| SCHEMBL9834425 | 0.72 | MAOA (0.36) | MAOAALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL9834940 | 0.72 | TTR (0.46) | MAOATTRALDH1A1KDM4EMAPT | |
| Acetic Acid SCHEMBL6239723 | 0.70 | TTR (0.55) | MAOATTRKDM5AIKBKBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4816479-A | HYPOTENSIVE AGENTS, DIURETICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4661607-A | ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |