Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834940 | 0.86 | TTR (0.46) | MAOAEGFRALDH1A1HPGDKDM4E | |
| SCHEMBL9836636 | 0.83 | PTGS2 (0.47) | MAOAALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL9836691 | 0.82 | DPP4 (0.38) | MAOAEGFRALDH1A1HPGDKDM4E | |
| SCHEMBL9836749 | 0.74 | SMN1; SMN2 (0.36) | MAOAEGFRPOLBSMN1; SMN2AR | |
| SCHEMBL9837354 | 0.74 | MAOA (0.37) | MAOAEGFRKDM4EMAPTKMT2A | |
| SCHEMBL9835513 | 0.72 | MAOA (0.47) | MAOAALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL9837184 | 0.66 | ESR1 (0.52) | MAOAEGFR | |
| SCHEMBL9835772 | 0.66 | ESR2 (0.54) | MAOAEGFRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10871145 | 0.66 | MGAM (0.42) | MAOAALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL10515427 | 0.65 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4816479-A | HYPOTENSIVE AGENTS, DIURETICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4661607-A | ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |