Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835131 | 0.80 | TSHR (0.41) | ALDH1A1KDM4EHPGDL3MBTL1TSHR | |
| SCHEMBL9836723 | 0.77 | KDM4E (0.39) | ALDH1A1KDM4EHPGDL3MBTL1TSHR | |
| SCHEMBL9835663 | 0.73 | TBXAS1 (0.43) | ALDH1A1KDM4EHPGDL3MBTL1TSHR | |
| SCHEMBL9835838 | 0.72 | KDM4E (0.35) | ALDH1A1KDM4EHPGDL3MBTL1LMNA | |
| SCHEMBL9835177 | 0.71 | TBXAS1 (0.53) | ALDH1A1KDM4EL3MBTL1TDP1GAA | |
| SCHEMBL9722754 | 0.70 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDL3MBTL1TSHR | |
| SCHEMBL10775514 | 0.69 | TBXAS1 (0.40) | ALDH1A1KDM4EHPGDL3MBTL1LMNA | |
| SCHEMBL7595087 | 0.68 | CNR2 (0.38) | ALDH1A1KDM4EHPGDL3MBTL1TSHR | |
| SCHEMBL31090834 | 0.68 | CA12 (0.50) | ALDH1A1KDM4EHPGDL3MBTL1TSHR | |
| SCHEMBL7911204 | 0.68 | CA12 (0.50) | ALDH1A1KDM4EHPGDL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |