SCHEMBL9836050

SCHEMBL9836050

C=C(C)C(OC(=O)Nc1cc(OCCCCCC)c(Cl)cc1Cl)C(=O)OCC(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.41
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
EBP Q15125 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
THRB P10828 5/20 0.37
THRA P10827 2/20 0.37
MAPT P10636 2/20 0.35
RECQL P46063 1/20 0.35
PTPN1 P18031 1/20 0.35
MAOA P21397 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ASAH1 Q13510 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9837424 0.86 SMN1; SMN2 (0.42) L3MBTL1TSHRLMNAEBPSIGMAR1
SCHEMBL9837299 0.86 SMN1; SMN2 (0.42) L3MBTL1TSHRLMNAEBPSIGMAR1
SCHEMBL9834024 0.86 SMN1; SMN2 (0.42) L3MBTL1TSHRLMNAEBPSIGMAR1
SCHEMBL9836102 0.86 SMN1; SMN2 (0.42) L3MBTL1TSHRLMNAEBPSIGMAR1
SCHEMBL9835684 0.85 SMN1; SMN2 (0.43) L3MBTL1TSHRALDH1A1LMNAEBP
SCHEMBL9836957 0.84 TSHR (0.39) L3MBTL1TSHRALDH1A1LMNANPSR1
SCHEMBL9836744 0.84 GAA (0.44) L3MBTL1TSHRALDH1A1LMNANPSR1
SCHEMBL9836716 0.81 RORC (0.41) L3MBTL1TSHRALDH1A1LMNANPSR1
SCHEMBL9836348 0.78 RORC (0.37) L3MBTL1TSHRALDH1A1LMNANPSR1
SCHEMBL11515924 0.76 THRB (0.49) L3MBTL1TSHRALDH1A1LMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed