Potassium Ion

Potassium Ion

SCHEMBL9835730

O=C([O-])C1(C(=O)[O-])CCC(C(=O)[O-])(C(=O)[O-])O1.[K+].[K+].[K+].[K+]

nearest known ligand 0.32

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Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.32
FAHD1 Q6P587 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11547580 0.72
SCHEMBL6401703 0.69 FFAR3 (0.38)
Potassium Ion SCHEMBL16910245 0.65 CA4 (0.38) CA4FAHD1
Potassium Ion SCHEMBL7907680 0.63
Potassium Ion SCHEMBL9870557 0.61
Oxalic Acid SCHEMBL29104844 0.60 CA4 (0.78) CA4FAHD1
SCHEMBL6757041 0.58
Potassium Ion SCHEMBL10906133 0.57
Oxalic Acid SCHEMBL29210048 0.57 CA4 (0.70) CA4FAHD1
Oxalic Acid SCHEMBL28832009 0.57 CA4 (0.70) CA4FAHD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0219154-B1 FURYL COMPOUNDS, THEIR USE AS FUNGICIDES AND THEIR PREPARATION SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-11-13 EP disclosed
EP-0219154-A2 Furyl compounds, their use as fungicides and their preparation SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-04-22 EP disclosed
US-4158635-A Detergent formulations containing tetrahydropyran or 1,4-dioxane polycarboxylates and method for using same MONSANTO COMPANY (US) 1979-06-19 US disclosed
US-4134902-A DETERGENT BUILDERS, CALCIUM AND MAGNESIUM SEQUESTRANTS, SCALE DISSOLVERS MONSANTO COMPANY (US) 1979-01-16 US disclosed
US-4102903-A DETERGENTS BUILDERS, SEQUESTERING AGENTS MONSANTO COMPANY (US) 1978-07-25 US disclosed
US-3923841-A Method of making tetra sodium and tetra potassium 2,2,5,5-tetrahydrofurantetracarboxylate MONSANTO CO 1975-12-02 US disclosed
US-3912765-A Tetrasodium and tetrapotassium salts of tetrahydrofuran-2,2,5,5-tetracarboxylic acid MONSANTO CO 1975-10-14 US disclosed