SCHEMBL9835708

SCHEMBL9835708

C=C(C)C(OC(=O)Nc1ccccc1)C(=O)OCC(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.52
ALDH1A1 P00352 4/20 0.52
HPGD P15428 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.42
HSD17B10 Q99714 1/20 0.42
DRD4 P21917 1/20 0.42
SLC6A2 P23975 1/20 0.42
CCKAR P32238 1/20 0.42
OPRM1 P35372 1/20 0.42
DRD3 P35462 1/20 0.42
SCN1A P35498 1/20 0.42
OPRK1 P41145 1/20 0.42
HTR2B P41595 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KCNH2 Q12809 1/20 0.42
SCN2A Q99250 1/20 0.42
SCN3A Q9NY46 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9837790 0.86 RAB9A (0.49) LMNAALDH1A1HPGDSMN1; SMN2HSD17B10
SCHEMBL9833996 0.85 SMN1; SMN2 (0.45) LMNAALDH1A1HPGDSMN1; SMN2HSD17B10
SCHEMBL9836062 0.82 NAPRT (0.47) LMNAALDH1A1HPGDSMN1; SMN2HSD17B10
SCHEMBL8602983 0.80 LMNA (0.74) LMNAALDH1A1HPGDSMN1; SMN2DRD4
SCHEMBL9837098 0.78 SMN1; SMN2 (0.56) LMNAALDH1A1HPGDSMN1; SMN2TSHR
SCHEMBL23115524 0.77 TSHR (0.49) LMNAALDH1A1HPGDSMN1; SMN2HSD17B10
SCHEMBL9837090 0.77 SMN1; SMN2 (0.46) LMNAHPGDSMN1; SMN2TSHRHTT
SCHEMBL9835875 0.77 SMN1; SMN2 (0.46) LMNAHPGDSMN1; SMN2TSHRHTT
SCHEMBL9835741 0.75 MAPT (0.48) LMNAALDH1A1HPGDSMN1; SMN2CYP1A2
SCHEMBL8203974 0.75 LMNA (0.53) LMNAALDH1A1HPGDSMN1; SMN2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1027069-C Process for producing oxazolidinedione derivative SAGAMI CHEM RES (JP) 1994-12-21 CN disclosed
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed
CN-86108416-A Oxazolidinedione derivative, process for producing the same, and herbicide containing the same 1987-07-29 CN disclosed