SCHEMBL9837783

SCHEMBL9837783

C=C(Cc1cc(Cl)cc(Cl)c1)C(OC(=O)Nc1cc(Cl)cc(Cl)c1)C(=O)OCC(C)C

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
MAPK1 P28482 2/20 0.41
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
RAB9A P51151 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 4/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
SLC13A3 Q8WWT9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9836787 0.81 MAPT (0.42) HPGDALOX15RAB9AL3MBTL1MAPT
SCHEMBL9837199 0.78 KLK7 (0.43) HPGDALOX15SMN1; SMN2MEN1KMT2A
SCHEMBL9836651 0.77 TSHR (0.41) TSHRMAPK1HTTLMNAHPGD
SCHEMBL11430603 0.77 TSHR (0.60) TSHRMAPK1HTTLMNAHPGD
SCHEMBL9835741 0.77 MAPT (0.48) TSHRMAPK1HTTLMNAHPGD
SCHEMBL10559825 0.73 KLK7 (0.43) HPGDALOX15SMN1; SMN2RAB9AMEN1
SCHEMBL9835786 0.71 HPGD (0.43) TSHRMAPK1HTTHPGDALOX15
SCHEMBL9358296 0.70 HPGD (0.71) TSHRMAPK1HTTLMNAHPGD
SCHEMBL6136789 0.69 ALDH1A1 (0.40) TSHRMAPK1HTTLMNAHPGD
SCHEMBL4417385 0.69 ALDH1A1 (0.40) TSHRMAPK1HTTLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed