Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835836 | 1.00 | EDNRA (0.46) | EDNRAKDM4EHSD17B10LMNATSHR | |
| SCHEMBL9833690 | 0.89 | EDNRA (0.46) | EDNRAKDM4ETP53MAPTTAS2R8 | |
| SCHEMBL9833684 | 0.89 | EDNRA (0.46) | EDNRAKDM4ETP53MAPTTAS2R8 | |
| SCHEMBL10754167 | 0.76 | EDNRA (0.49) | EDNRAKDM4EMAPTPPARGPPARD | |
| SCHEMBL10744651 | 0.75 | EDNRA (0.43) | EDNRAHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL9735514 | 0.73 | EDNRA (0.45) | EDNRAKDM4ELMNATSHRTP53 | |
| SCHEMBL18895700 | 0.72 | EDNRA (0.54) | EDNRALMNATSHRTP53MAPT | |
| SCHEMBL10753757 | 0.71 | GAA (0.50) | EDNRALMNATSHRMAPTALDH1A1 | |
| SCHEMBL11117907 | 0.71 | EDNRA (0.53) | EDNRAKDM4ELMNATSHRTP53 | |
| SCHEMBL9588694 | 0.70 | EDNRA (0.43) | EDNRALMNATP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343462-B1 | AMINOGUANIDINO AZINES | BAYER AG (DE) | 1991-12-11 | — | — | EP | claimed |