Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837046 | 0.89 | TBXAS1 (0.43) | TBXAS1CYP17A1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL9836736 | 0.77 | TBXAS1 (0.43) | TBXAS1NPC1RAB9A | |
| SCHEMBL9835558 | 0.76 | TBXAS1 (0.63) | TBXAS1CYP17A1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL9835771 | 0.71 | TBXAS1 (0.50) | TBXAS1CYP17A1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL9834596 | 0.70 | TBXAS1 (1.00) | TBXAS1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL9836537 | 0.70 | TBXAS1 (0.98) | TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL27690673 | 0.66 | ALDH1A1 (0.41) | TBXAS1CYP17A1CYP11B1CYP11B2NPC1 | |
| SCHEMBL9871950 | 0.66 | NPC1 (0.42) | TBXAS1NPC1RAB9A | |
| SCHEMBL9791461 | 0.65 | CYP17A1 (0.57) | CYP17A1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL9784397 | 0.63 | CYP17A1 (0.64) | CYP17A1CYP11B1CYP11B2CYP19A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |