Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.30 |
| ▸ | TDO2 | P48775 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871950 | 0.86 | NPC1 (0.42) | TBXAS1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9836161 | 0.77 | TBXAS1 (0.54) | TBXAS1NPC1RAB9A | |
| SCHEMBL9834753 | 0.69 | TBXAS1 (0.45) | TBXAS1HIF1ADHODH | |
| SCHEMBL21597427 | 0.67 | TBXAS1 (0.46) | TBXAS1NPC1RAB9APDK1ALDH1A1 | |
| SCHEMBL8637911 | 0.64 | AKR1C3 (0.46) | TBXAS1PDK1 | |
| SCHEMBL10439397 | 0.60 | MAPT (0.53) | TBXAS1ALDH1A1HIF1AMAPT | |
| SCHEMBL31221788 | 0.58 | ACHE (0.38) | NPC1RAB9AALDH1A1MAPTIDO1 | |
| SCHEMBL6427539 | 0.58 | FAAH (0.53) | — | |
| SCHEMBL367535 | 0.58 | FAAH (0.53) | — | |
| SCHEMBL5608206 | 0.58 | FAAH (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |