Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834510 | 0.84 | MAOA (0.59) | TTRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9835886 | 0.80 | AKR1C3 (0.57) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL9836863 | 0.74 | MAOA (0.64) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| Acetic Acid SCHEMBL30589868 | 0.71 | MAOA (0.57) | TTRALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL9282004 | 0.70 | MAOA (0.63) | ALDH1A1HPGDKDM4EHSD17B10MAOA | |
| SCHEMBL20317224 | 0.69 | AR (0.45) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL9834780 | 0.69 | ALDH1A1 (0.64) | TTRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9836010 | 0.69 | MAOA (0.59) | TTRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL20346671 | 0.68 | MAOA (0.56) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL9837177 | 0.68 | PTPN1 (0.48) | TTRMEN1KMT2AMAOAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4816479-A | HYPOTENSIVE AGENTS, DIURETICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4661607-A | ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0175376-A2 | Xanthone derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-03-26 | — | — | EP | disclosed |