SCHEMBL9836600

SCHEMBL9836600

CC(C)Oc1cc(N(F)C(=O)Cl)ccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 2/20 0.40
KCNQ3 O43525 1/20 0.38
KCNQ2 O43526 1/20 0.38
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
CCR1 P32246 1/20 0.36
BACE1 P56817 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.35
CSNK2A1 P68400 2/20 0.35
KMO O15229 2/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.34
MAP2 P11137 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
PTGDR Q13258 1/20 0.34
ACLY P53396 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835945 0.87 KCNQ3 (0.38) RORCKCNQ3KCNQ2RXRARXRB
SCHEMBL9834552 0.84 RXRA (0.36) RORCKCNQ3KCNQ2RXRARXRB
SCHEMBL9836953 0.84 RORC (0.41) RORCKCNQ3KCNQ2RXRARXRB
SCHEMBL9836984 0.83 GRM4 (0.42) MEN1ALDH1A1KMT2AKMO
SCHEMBL9836438 0.81 FBP1 (0.32)
SCHEMBL9837234 0.79 RORC (0.40) RORCKCNQ3KCNQ2CCR1MEN1
SCHEMBL19088276 0.72 CSNK2A1 (0.43) RORCCSNK2A1ACLYP2RX7
SCHEMBL9836314 0.72 GRM4 (0.42) BACE1MAPK1
SCHEMBL9836319 0.71 EGFR (0.40) MEN1ALDH1A1KMT2AGAAMAPK1
SCHEMBL15658321 0.70 TSHR (0.53) RORCRXRARXRBRXRGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed