Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835405 | 0.79 | CES2 (0.41) | SMN1; SMN2ALDH1A1LMNAKDM4EMAPK1 | |
| SCHEMBL20560331 | 0.78 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7949240 | 0.74 | NPSR1 (0.45) | EGFRCYP2C9CYP2D6HIF1ASMN1; SMN2 | |
| SCHEMBL18805967 | 0.71 | TYR (0.44) | CYP2C9CYP2D6HIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12922764 | 0.71 | TYR (0.44) | CYP2C9CYP2D6HIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3962970 | 0.69 | ALDH1A1 (0.49) | EGFRERBB2CYP2C9CYP2D6HIF1A | |
| P-Cymene SCHEMBL29129736 | 0.69 | ACHE (0.47) | CYP2C9CYP2D6HIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16021747 | 0.69 | ADRB2 (0.50) | HIF1ASMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL1505402 | 0.69 | CYP2C9 (0.53) | EGFRERBB2CYP2C9CYP2D6HIF1A | |
| SCHEMBL10080954 | 0.68 | ALDH1A1 (0.69) | CYP2C9CYP2D6HIF1ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241559-B1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4983751-A | Chemical intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4818272-A | NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-04-04 | — | — | US | disclosed |
| EP-0241559-A1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-10-21 | — | — | EP | disclosed |