Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835526 | 0.85 | BCHE (0.44) | BCHEACHEEPHX2KMT2ANPC1 | |
| SCHEMBL28712083 | 0.81 | LTB4R2 (0.63) | BCHEACHEEPHX2MEN1KMT2A | |
| SCHEMBL4924149 | 0.81 | LTB4R2 (0.63) | BCHEACHEEPHX2MEN1KMT2A | |
| SCHEMBL29450616 | 0.81 | LTB4R2 (0.63) | BCHEACHEEPHX2MEN1KMT2A | |
| SCHEMBL7761239 | 0.80 | NPC1 (0.72) | BCHEACHEEPHX2MEN1KMT2A | |
| SCHEMBL14946877 | 0.80 | NPC1 (0.72) | BCHEACHEEPHX2MEN1KMT2A | |
| SCHEMBL8017184 | 0.80 | NPC1 (0.72) | BCHEACHEEPHX2MEN1KMT2A | |
| SCHEMBL4398063 | 0.80 | LTB4R2 (0.64) | BCHEACHEEPHX2NPC1LMNA | |
| SCHEMBL2945289 | 0.79 | TSHR (0.47) | EPHX2MEN1KMT2ALMNATSHR | |
| SCHEMBL28217434 | 0.79 | LMNA (0.68) | BCHEACHEEPHX2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0200377-A2 | Hydroxamates | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |