Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836712 | 0.85 | BCHE (0.49) | BCHEACHENPC1MAPK1LMNA | |
| SCHEMBL9835801 | 0.79 | LMNA (0.34) | LMNAHSD17B10ALOX15TSHRFAAH | |
| SCHEMBL9836015 | 0.79 | ALOX5 (0.45) | BCHEACHENPC1ALOX5KDM4A | |
| SCHEMBL7425833 | 0.71 | ALOX5 (0.61) | NPC1MAPK1LMNAHSD17B10ALOX15 | |
| SCHEMBL28239431 | 0.70 | ALDH1A1 (0.46) | NPC1MAPK1LMNAHSD17B10ALOX15 | |
| SCHEMBL9836621 | 0.70 | LMNA (0.35) | LMNAHSD17B10ALOX15TSHRFAAH | |
| SCHEMBL7238328 | 0.69 | EPHX2 (0.60) | LMNAHSD17B10ALOX15FAAHEPHX2 | |
| SCHEMBL9506847 | 0.69 | TNNC1 (0.42) | BCHEACHEFAAHEPHX2CNR1 | |
| SCHEMBL9506854 | 0.69 | TNNC1 (0.42) | BCHEACHEFAAHEPHX2CNR1 | |
| SCHEMBL9136025 | 0.68 | NPC1 (0.60) | BCHEACHENPC1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0200377-A2 | Hydroxamates | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |