SCHEMBL9836787

SCHEMBL9836787

C=C(Cc1ccc(Cl)cc1)C(OC(=O)Nc1cc(Cl)cc(Cl)c1)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
KLK7 P49862 11/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9837199 0.84 KLK7 (0.43) MAPTKLK7HPGDALOX15ALDH1A1
SCHEMBL10559825 0.81 KLK7 (0.43) MAPTKLK7HPGDALOX15RAB9A
SCHEMBL9837783 0.81 TSHR (0.41) MAPTHPGDALOX15RAB9AL3MBTL1
SCHEMBL9835786 0.80 HPGD (0.43) MAPTHPGDALOX15RAB9AL3MBTL1
SCHEMBL9835172 0.79 MAPT (0.52) MAPTHPGDRAB9AL3MBTL1ALDH1A1
SCHEMBL9835245 0.75 MEN1 (0.46) MAPTHPGDALOX15RAB9AL3MBTL1
SCHEMBL9837472 0.75 MAPT (0.48) MAPTHPGDRAB9AL3MBTL1ALDH1A1
SCHEMBL9836424 0.75 MAPT (0.52) MAPTHPGDALOX15RAB9AL3MBTL1
SCHEMBL9835915 0.74 MAPT (0.46) MAPTHPGDRAB9AL3MBTL1ALDH1A1
SCHEMBL27368858 0.73 HPGD (0.42) MAPTHPGDALOX15RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed