Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837630 | 0.87 | MEN1 (0.47) | MAP1LC3BHPGDSMN1; SMN2TSHRLMNA | |
| SCHEMBL9834910 | 0.85 | KMT2A (0.43) | MAP1LC3BHPGDSMN1; SMN2HSD17B10TSHR | |
| SCHEMBL9845968 | 0.80 | MAP1LC3B (0.38) | MAP1LC3BHPGDSMN1; SMN2HSD17B10TSHR | |
| SCHEMBL9837566 | 0.77 | GAA (0.42) | MAP1LC3BHPGDSMN1; SMN2HSD17B10TSHR | |
| SCHEMBL9837769 | 0.76 | MAPT (0.46) | MAP1LC3BHPGDSMN1; SMN2HSD17B10TSHR | |
| SCHEMBL9835656 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL428432 | 0.70 | MAP1LC3B (0.55) | MAP1LC3BHPGDSMN1; SMN2LMNAPOLB | |
| SCHEMBL9836885 | 0.69 | GRM2 (0.42) | MAP1LC3BHPGDLMNAMEN1KMT2A | |
| SCHEMBL21795165 | 0.65 | MAP1LC3B (0.68) | MAP1LC3BHPGDSMN1; SMN2TSHRRXFP1 | |
| SCHEMBL21821615 | 0.64 | MAP1LC3B (0.66) | MAP1LC3BHPGDSMN1; SMN2TSHRRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261674-B1 | A CYCLOHEXANEDIONE DERIVATIVE AND A PROCESS FOR PRODUCING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1991-06-12 | — | — | EP | claimed |
| US-4863925-A | SUBSTITUTED | NIHON NOHYAKU CO., LTD. (JP) | 1989-09-05 | — | — | US | claimed |
| EP-0261674-A1 | A cyclohexanedione derivative and a process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 1988-03-30 | — | — | EP | claimed |