Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ERN1 | O75460 | 4/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6067949 | 0.83 | ERN1 (0.49) | PRMT6TAAR1PTPN1ERN1KEAP1 | |
| SCHEMBL9454526 | 0.79 | PRMT6 (0.63) | PRMT6TAAR1ERN1KEAP1ADORA3 | |
| SCHEMBL27569385 | 0.78 | PRMT6 (0.49) | PRMT6TAAR1ERN1KEAP1ADORA3 | |
| SCHEMBL120565 | 0.76 | TAAR1 (0.66) | PRMT6TAAR1ERN1KEAP1ADORA3 | |
| SCHEMBL4135657 | 0.75 | PRMT6 (0.43) | PRMT6TAAR1KEAP1ADORA3ADORA2A | |
| SCHEMBL19662062 | 0.72 | TAAR1 (0.58) | PRMT6TAAR1PTPN1ERN1KEAP1 | |
| SCHEMBL30060639 | 0.72 | KEAP1 (0.58) | PRMT6TAAR1ERN1KEAP1ADORA3 | |
| SCHEMBL418106 | 0.72 | KEAP1 (0.58) | PRMT6TAAR1ERN1KEAP1ADORA3 | |
| SCHEMBL1346211 | 0.69 | PRMT6 (0.59) | PRMT6TAAR1ERN1KEAP1ADORA3 | |
| SCHEMBL419195 | 0.69 | TAAR1 (0.61) | TAAR1ERN1KEAP1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304139-B1 | PROCESS FOR MAKING 5-HYDROXY-3-HYDROXYMETHYL-2-PHENYLFURAN DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-11 | — | — | EP | disclosed |
| EP-0304139-A1 | Process for making 5-hydroxy-3-hydroxymethyl-2-phenylfuran derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | disclosed |