Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.68 |
| ▸ | AHR | P35869 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GPR3 | P46089 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18201434 | 0.85 | KIF11 (0.64) | KIF11AHRALDH1A1GPR3HSD17B10 | |
| SCHEMBL24973490 | 0.81 | KIF11 (0.58) | KIF11AHRALDH1A1GPR3HSD17B10 | |
| SCHEMBL1246016 | 0.81 | KIF11 (0.68) | KIF11AHRALDH1A1GPR3HSD17B10 | |
| SCHEMBL7963280 | 0.81 | KIF11 (1.00) | KIF11AHRALDH1A1GPR3HSD17B10 | |
| SCHEMBL29953653 | 0.81 | KIF11 (1.00) | KIF11AHRALDH1A1GPR3HSD17B10 | |
| SCHEMBL21668968 | 0.80 | KIF11 (0.57) | KIF11AHRALDH1A1GPR3HSD17B10 | |
| SCHEMBL9839009 | 0.79 | PTGS2 (0.50) | KIF11MAPT | |
| SCHEMBL27750624 | 0.77 | KIF11 (0.62) | KIF11AHRALDH1A1GPR3HSD17B10 | |
| Carbazole SCHEMBL27568363 | 0.74 | ALDH1A1 (0.70) | KIF11AHRALDH1A1GPR3HSD17B10 | |
| SCHEMBL8124645 | 0.74 | KIF11 (0.64) | KIF11AHRALDH1A1GPR3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028603-A | Platelet-Activating Factor Antagonist; Useful In Treatment Of Inflammatory Diseases, Allergic Diseases, Asthma, Respiratory System Disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0316456-A1 | ESTER-SUBSTITUTED THIENOTRIAZOLODIAZEPINE COMPOUNDS AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-24 | — | — | EP | disclosed |