Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837769 | 0.79 | MAPT (0.46) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL9845996 | 0.65 | MAPT (0.43) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL9845971 | 0.60 | TDP1 (0.38) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL14125492 | 0.59 | POLB (0.59) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL1177395 | 0.58 | POLB (1.00) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL21218882 | 0.57 | CHRM5 (0.54) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL15500328 | 0.56 | CHRM5 (0.46) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL14985347 | 0.56 | CHRM5 (0.46) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL9837566 | 0.56 | GAA (0.42) | MAPTPOLBKMT2ANPSR1ALDH1A1 | |
| SCHEMBL7751093 | 0.56 | POLB (0.58) | MAPTPOLBTDP1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261674-B1 | A CYCLOHEXANEDIONE DERIVATIVE AND A PROCESS FOR PRODUCING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1991-06-12 | — | — | EP | claimed |
| US-4863925-A | SUBSTITUTED | NIHON NOHYAKU CO., LTD. (JP) | 1989-09-05 | — | — | US | claimed |
| EP-0261674-A1 | A cyclohexanedione derivative and a process for producing the same | NIHON NOHYAKU CO., LTD. (JP) | 1988-03-30 | — | — | EP | claimed |