Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.38 |
| ▸ | POLB | P06746 | 11/20 | 0.38 |
| ▸ | MAPT | P10636 | 10/20 | 0.38 |
| ▸ | PKM | P14618 | 9/20 | 0.38 |
| ▸ | LMNA | P02545 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | RECQL | P46063 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845996 | 0.82 | MAPT (0.43) | TDP1SHMT2ALDH1A1POLBMAPT | |
| SCHEMBL9845987 | 0.79 | MAP1LC3B (0.43) | ALDH1A1POLBMAPTLMNATSHR | |
| SCHEMBL9845959 | 0.75 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL9837769 | 0.69 | MAPT (0.46) | TDP1SHMT2ALDH1A1POLBMAPT | |
| SCHEMBL1782631 | 0.62 | POLB (0.56) | TDP1SHMT2ALDH1A1POLBMAPT | |
| SCHEMBL9837030 | 0.60 | MAPT (0.38) | TDP1SHMT2ALDH1A1POLBMAPT | |
| SCHEMBL9845961 | 0.60 | MAP1LC3B (0.34) | MAPTLMNATSHRCYP2C9CYP2C19 | |
| SCHEMBL12648261 | 0.58 | POLB (0.54) | TDP1ALDH1A1POLBMAPTPKM | |
| SCHEMBL1177395 | 0.58 | POLB (1.00) | TDP1ALDH1A1POLBMAPTMAPK1 | |
| SCHEMBL7158584 | 0.57 | ALDH1A1 (0.44) | TDP1ALDH1A1POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414952-A1 | Dithiolane derivatives | NIHON NOHYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |