Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | POLB | P06746 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 4/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845971 | 0.82 | TDP1 (0.38) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL9837769 | 0.74 | MAPT (0.46) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL9837030 | 0.65 | MAPT (0.38) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL1177395 | 0.62 | POLB (1.00) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL1782631 | 0.61 | POLB (0.56) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL14125492 | 0.60 | POLB (0.59) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL7687762 | 0.60 | POLB (0.50) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL1177894 | 0.59 | POLB (0.62) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL12648261 | 0.59 | POLB (0.54) | MAPTPOLBTDP1KMT2ANPSR1 | |
| SCHEMBL7689218 | 0.58 | ALDH1A1 (0.55) | MAPTPOLBTDP1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414952-A1 | Dithiolane derivatives | NIHON NOHYAKU CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |