SCHEMBL9837348

SCHEMBL9837348

O=C(Cl)N(Cl)c1ccc(Cl)cc1F

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FSCN1 Q16658 1/20 0.40
KMO O15229 2/20 0.39
KMT2A Q03164 3/20 0.38
PPARG P37231 4/20 0.36
PPARA Q07869 4/20 0.36
GRM2 Q14416 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
CYP11B2 P19099 3/20 0.35
CYP11B1 P15538 2/20 0.35
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
MEN1 O00255 1/20 0.33
TSHR P16473 1/20 0.33
CASP1 P29466 1/20 0.33
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20560161 0.75 ALDH1A1 (0.47) KMT2ARAB9ASMN1; SMN2NPC1HPGD
SCHEMBL3883604 0.73 FSCN1 (0.50) FSCN1KMOKMT2APPARGPPARA
SCHEMBL4115500 0.73 PPARG (0.42) FSCN1KMOKMT2APPARGPPARA
SCHEMBL1504095 0.71 KMT2A (0.38) FSCN1KMT2APPARGPPARASIRT2
SCHEMBL28069620 0.70 CES2 (0.46) FSCN1KMOKMT2APPARGPPARA
SCHEMBL17601353 0.69 FSCN1 (0.39) FSCN1KMOKMT2APPARGPPARA
SCHEMBL645757 0.68 ALDH1A1 (0.54) KMT2ARAB9ASMN1; SMN2NPC1HPGD
SCHEMBL10494526 0.68 KMT2A (0.44) FSCN1KMT2ASIRT2CYP11B2CYP11B1
SCHEMBL21199998 0.68 KMO (0.40) KMOCYP11B2CYP11B1
SCHEMBL10485955 0.67 FSCN1 (0.56) FSCN1SMN1; SMN2HPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed