Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 16/20 | 0.59 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836523 | 0.89 | TBXAS1 (0.74) | TBXAS1 | |
| SCHEMBL9835155 | 0.86 | TBXAS1 (0.79) | TBXAS1EGLN3ALDH1A1GAA | |
| SCHEMBL9836019 | 0.83 | TBXAS1 (0.72) | TBXAS1EGLN3ALDH1A1GAA | |
| SCHEMBL9837297 | 0.83 | TBXAS1 (0.64) | TBXAS1EGLN3ALDH1A1GAA | |
| SCHEMBL9835184 | 0.82 | TBXAS1 (0.61) | TBXAS1ALDH1A1GAA | |
| Imitrodast SCHEMBL166460 | 0.74 | TBXAS1 (1.00) | TBXAS1 | |
| Imitrodast SCHEMBL99497 | 0.73 | TBXAS1 (0.98) | TBXAS1 | |
| SCHEMBL9834048 | 0.72 | TBXAS1 (0.71) | TBXAS1 | |
| Imitrodast SCHEMBL8156405 | 0.71 | TBXAS1 (0.81) | TBXAS1ALDH1A1 | |
| SCHEMBL9836779 | 0.71 | TBXAS1 (0.76) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | claimed |