Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4553044 | 0.76 | AR (0.51) | ARCA12CA9CA1CA3 | |
| SCHEMBL1771268 | 0.72 | AR (0.70) | AR | |
| SCHEMBL10694157 | 0.69 | CHKA (0.41) | DHFRMAPT | |
| SCHEMBL5386689 | 0.69 | TERT (0.58) | DHFRMAPTACHE | |
| SCHEMBL22778032 | 0.69 | CA12 (0.48) | ARCA12CA9CA1CA3 | |
| SCHEMBL31426086 | 0.69 | CA12 (0.48) | ARCA12CA9CA1CA3 | |
| SCHEMBL10935728 | 0.69 | INSR (0.46) | MAPK1DHFRMAPT | |
| SCHEMBL7854069 | 0.69 | CA12 (0.52) | CA12CA9CA1CA3CA4 | |
| SCHEMBL1775364 | 0.69 | KIF11 (0.45) | ARCA12CA9CA1CA3 | |
| SCHEMBL462461 | 0.69 | KDM4E (0.65) | CA12CA9CA1CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156261-B1 | FLUOROGENIC DIHYDROQUINOLONE AND DIHYDROCOUMARIN INDICATORS FOR HYDROGEN PEROXIDE | MILES INC. (US) | 1991-11-27 | — | — | EP | disclosed |
| US-4794079-A | PEROXIDASE | MILES INC. (US) | 1988-12-27 | — | — | US | disclosed |
| US-4558130-A | FLUORESCENCE ON OXIDATION BY HYDROGEN PEROXIDE; PEROXIDASE DETERMINATION | MILES LABORATORIES, INC. (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0156261-A2 | Fluorogenic dihydroquinolone and dihydrocoumarin indicators for hydrogen peroxide | MILES INC. (US) | 1985-10-02 | — | — | EP | disclosed |