Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | GLA | P06280 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 9/20 | 0.52 |
| ▸ | CA9 | Q16790 | 9/20 | 0.52 |
| ▸ | CA1 | P00915 | 8/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL28369375 | 0.79 | ALDH1A1 (0.94) | KDM4EALDH1A1GLAL3MBTL1CA12 | |
| SCHEMBL142022 | 0.79 | ALDH1A1 (1.00) | KDM4EALDH1A1GLAL3MBTL1CA12 | |
| SCHEMBL29440642 | 0.79 | ALDH1A1 (1.00) | KDM4EALDH1A1GLAL3MBTL1CA12 | |
| SCHEMBL17145062 | 0.79 | MEN1 (0.71) | KDM4EALDH1A1GLAL3MBTL1HPGD | |
| SCHEMBL8813329 | 0.79 | IGLV6-57 (0.47) | KDM4EALDH1A1GLAL3MBTL1SRD5A1 | |
| SCHEMBL16296942 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1GLAL3MBTL1CA12 | |
| Bromide SCHEMBL31261167 | 0.78 | ALDH1A1 (0.97) | KDM4EALDH1A1GLAL3MBTL1CA12 | |
| SCHEMBL3950391 | 0.77 | ALDH1A1 (0.68) | KDM4EALDH1A1GLAL3MBTL1CA12 | |
| SCHEMBL1752667 | 0.77 | ALDH1A1 (0.70) | KDM4EALDH1A1GLAL3MBTL1CA12 | |
| SCHEMBL15138689 | 0.76 | SLC16A3 (0.70) | KDM4EALDH1A1CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11965881-B2 | Nanosensors and methods for detection of biological markers | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2024-04-23 | — | — | US | disclosed |
| US-20240125800-A1 | NANOSENSORS FOR RAPID IDENTIFICATION OF LUNG CONDITIONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2024-04-18 | — | — | US | disclosed |
| US-11952612-B2 | Protease sensor molecules | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2024-04-09 | — | — | US | disclosed |
| WO-2024010609-A1 | PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS | HAWKEYE BIO, LIMITED (IE) | 2024-01-11 | — | — | WO | disclosed |
| EP-3538665-B1 | PROTEASE SENSOR MOLECULES | PPB TECH PTY LTD (AU) | 2024-01-03 | — | — | EP | disclosed |
| EP-4271651-A1 | PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS | HAWKEYE BIO, LIMITED (IE) | 2023-11-08 | — | — | EP | disclosed |
| US-20230258640-A1 | PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS | HAWKEYE BIO, LIMITED (IE) | 2023-08-17 | — | — | US | disclosed |
| WO-2022147179-A1 | NANOSENSORS FOR RAPID IDENTIFICATION OF LUNG CONDITIONS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2022-07-07 | — | — | WO | disclosed |
| WO-2022147171-A1 | PRISTINE GRAPHENE BASED BIOSENSOR FOR BIOMARKER DETECTION AND RELATED CORE PARTICLES, MATERIALS COMPOSITIONS METHODS AND SYSTEMS | HAWKEYE BIO, LIMITED (US) | 2022-07-07 | — | — | WO | disclosed |
| US-11318470-B2 | Microfluidics-based nanobiosensors and devices | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2022-05-03 | — | — | US | disclosed |
| US-20120157824-A1 | MRI AND OPTICAL ASSAYS FOR PROTEASES | NANOSCALE CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
| WO-2012050896-A2 | PROTEASE SELECTIVE SUPRAMOLECULAR ASSEMBLIES | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-04-19 | — | — | WO | disclosed |
| WO-2012034061-A2 | COMBINATION METHODS OF DIAGNOSING CANCER IN A PATIENT | TRAXXSSON, LLC (US) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011028698-A2 | MRI AND OPTICAL ASSAYS FOR PROTEASES | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-03-10 | — | — | WO | disclosed |
| US-20110014125-A1 | PROTEASE ASSAY | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-01-20 | — | — | US | disclosed |
| EP-2260108-A2 | PROTEASE ASSAY | Kansas State University Research Foundation (US) | 2010-12-15 | — | — | EP | disclosed |
| US-20100040978-A1 | PHOTOSENSITIVE LITHOGRAPHIC PRINTING PLATE MATERIAL | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2010-02-18 | — | — | US | disclosed |
| WO-2009111470-A2 | PROTEASE ASSAY | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2009-09-11 | — | — | WO | disclosed |
| US-6844136-B1 | Photopolymerizable mixture and recording material prepared therewith | AGFA-GEVAERT (BE) | 2005-01-18 | — | — | US | disclosed |
| EP-1079276-A1 | Photopolymerisable mixture and recording material prepared therewith | AGFA-GEVAERT naamloze vennootschap (BE) | 2001-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110014125-A1 | PROTEASE ASSAY | PREP, TMPRSS15, PRSS3 | KDM4E 3846/4885ALDH1A1 3771/4885GLA 318/4885 |
| US-20120157824-A1 | MRI AND OPTICAL ASSAYS FOR PROTEASES | PREP, HPN, ADAM9 | KDM4E 4459/4885ALDH1A1 4179/4885GLA 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.