Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149366 | 0.88 | PTGER1 (0.62) | L3MBTL1TDP1LMNAMAPK1HTT | |
| SCHEMBL77988 | 0.86 | KDM4E (0.50) | L3MBTL1TDP1LMNAMAPK1HTT | |
| SCHEMBL29239975 | 0.80 | PTPN11 (0.67) | PTGER1KDM4EALDH1A1SMN1; SMN2THRB | |
| SCHEMBL27528318 | 0.78 | ADRB2 (0.54) | LMNAMAPK1PTGER1KDM4EALDH1A1 | |
| SCHEMBL23041052 | 0.77 | L3MBTL1 (0.50) | L3MBTL1TDP1LMNAMAPK1HTT | |
| SCHEMBL28053324 | 0.77 | MAPT (0.50) | L3MBTL1TDP1LMNAMAPK1HTT | |
| SCHEMBL14241162 | 0.77 | NR1H4 (0.53) | L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL15473251 | 0.77 | ADRB2 (0.49) | L3MBTL1TDP1LMNAMAPK1KDM4E | |
| SCHEMBL1133183 | 0.76 | PTGER1 (0.65) | L3MBTL1TDP1LMNAMAPK1HTT | |
| SCHEMBL13531027 | 0.76 | THRA (0.55) | L3MBTL1TDP1LMNAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462150-A1 | NOVEL ARYLOXY ALKYL AMINES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM. | LAEVOSAN GMBH & CO KG (AT) | 1991-12-27 | — | — | EP | disclosed |
| WO-1990010628-A1 | NOVEL ARYLOXY ALKYL AMINES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM | LAEVOSAN-GESELLSCHAFT MBH (AT) | 1990-09-20 | — | — | WO | disclosed |