Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.49 |
| ▸ | HTR3B | O95264 | 3/20 | 0.49 |
| ▸ | HTR3A | P46098 | 3/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | HTR5A | P47898 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TERT | O14746 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22790262 | 0.90 | HTR3E (0.51) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL17420335 | 0.87 | TERT (0.56) | HSD17B10TSHRALDH1A1MGAMABL1 | |
| SCHEMBL17420285 | 0.87 | TERT (0.60) | HSD17B10TSHRALDH1A1MGAMABL1 | |
| SCHEMBL17420313 | 0.83 | SLC16A3 (0.52) | TSHRALDH1A1MGAMKDM4E | |
| SCHEMBL17420314 | 0.83 | KDM4E (0.52) | HTR3ATSHRALDH1A1MGAMABL1 | |
| SCHEMBL17420281 | 0.78 | PIM2 (0.51) | TSHRUSP2ALDH1A1MGAMKDM4E | |
| SCHEMBL17420317 | 0.78 | HRH3 (0.43) | TSHRUSP2MGAMTERT | |
| SCHEMBL17420283 | 0.77 | PIM2 (0.48) | HSD17B10TSHRALDH1A1HDAC3MGAM | |
| SCHEMBL8727055 | 0.77 | HDAC3 (0.60) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL21044592 | 0.77 | ADRB1 (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |
| US-4686221-A | Quinolinecarboxylic acid compounds and antimicrobial agent containing the same | KANEBO, LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0220523-A2 | Novel quinolinecarboxylic acid compounds, processes for preparing them, pharmaceutical composition and use | KANEBO, LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |