Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 5/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.30 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298216 | 0.73 | ACHE (0.39) | ALOX5PTGS2HMGCR | |
| SCHEMBL9128562 | 0.72 | ALDH1A1 (0.47) | NAAA | |
| SCHEMBL9766944 | 0.71 | CYP3A4 (0.34) | NAAAALOX5PTGS2HMGCR | |
| SCHEMBL9838197 | 0.68 | F13A1 (0.46) | PTGS2 | |
| SCHEMBL9325223 | 0.67 | EP300 (0.39) | NAAA | |
| SCHEMBL9746758 | 0.67 | PDCD4 (0.34) | NAAA | |
| SCHEMBL10579063 | 0.66 | PDCD4 (0.45) | — | |
| SCHEMBL10578726 | 0.66 | PDCD4 (0.42) | — | |
| SCHEMBL10579069 | 0.66 | PDCD4 (0.45) | — | |
| SCHEMBL10575180 | 0.66 | PDCD4 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059611-A | Treating psoriasis and modifying calcium homeostatis | ALLERGAN, INC. (US) | 1991-10-22 | — | — | US | disclosed |