Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869891 | 1.00 | TSHR (0.51) | TSHRLTA4HRAB9AHSD17B10LMNA | |
| SCHEMBL9838876 | 0.81 | TSHR (0.74) | TSHRRAB9AHSD17B10LMNAPRMT5 | |
| SCHEMBL9839972 | 0.81 | TSHR (0.74) | TSHRRAB9AHSD17B10LMNAPRMT5 | |
| SCHEMBL9838885 | 0.81 | TSHR (0.74) | TSHRRAB9AHSD17B10LMNAPRMT5 | |
| SCHEMBL9869970 | 0.79 | PRMT5 (0.51) | TSHRLTA4HRAB9AHSD17B10PRMT5 | |
| SCHEMBL7271333 | 0.78 | KDM4E (0.67) | TSHRLTA4HRAB9AHSD17B10MAPK1 | |
| SCHEMBL8717637 | 0.77 | TSHR (0.47) | TSHRLTA4HRAB9AHSD17B10LMNA | |
| SCHEMBL11538263 | 0.76 | TSHR (0.68) | TSHRRAB9AHSD17B10LMNAMAPK1 | |
| SCHEMBL15176767 | 0.76 | TSHR (0.57) | TSHRLMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL4663018 | 0.74 | LTA4H (0.60) | TSHRLTA4HRAB9AHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002732-A1 | NOVEL OPTICALLY ACTIVE BASIC ETHERS, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-03-07 | — | — | WO | disclosed |