Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 5/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837575 | 0.84 | DPP4 (0.55) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9867142 | 0.84 | DPP4 (0.56) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9838619 | 0.83 | DPP4 (0.56) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL9838610 | 0.82 | DPP4 (0.56) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9686492 | 0.81 | DHFR (0.59) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9837392 | 0.81 | LMNA (0.61) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9668899 | 0.81 | DPP4 (0.60) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9672074 | 0.81 | DPP4 (0.61) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9670599 | 0.80 | DPP4 (0.60) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9670589 | 0.79 | DPP4 (0.59) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |
| US-4571396-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-02-18 | — | — | US | disclosed |
| EP-0159174-A2 | Substituted naphthyridine-, quinoline- and benzoxazine- carboxylic acids as antibacterial agents and processes for their production | WARNER-LAMBERT COMPANY (US) | 1985-10-23 | — | — | EP | disclosed |