Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837856 | 0.94 | RAB9A (0.49) | EPHX1GAARAB9AEPHX2MEN1 | |
| SCHEMBL9837842 | 0.93 | EPHX1 (0.51) | EPHX1GAARAB9AEPHX2MEN1 | |
| SCHEMBL9838879 | 0.81 | GAA (0.46) | EPHX1GAARAB9AEPHX2LMNA | |
| SCHEMBL9838897 | 0.78 | EPHX1 (0.51) | EPHX1GAARAB9AEPHX2MEN1 | |
| SCHEMBL9837559 | 0.77 | RAB9A (0.54) | EPHX1GAARAB9AEPHX2MEN1 | |
| SCHEMBL9838913 | 0.76 | RAB9A (0.49) | EPHX1GAARAB9AEPHX2MEN1 | |
| SCHEMBL9837558 | 0.75 | RAB9A (0.51) | EPHX1GAARAB9AEPHX2MEN1 | |
| SCHEMBL9838968 | 0.75 | EPHX1 (0.48) | EPHX1GAARAB9AEPHX2KMT2A | |
| SCHEMBL31488958 | 0.73 | LTA4H (0.42) | EPHX1GAARAB9ALMNASSTR4 | |
| SCHEMBL25464169 | 0.71 | LMNA (0.50) | EPHX1RAB9AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276122-B1 | CYCLOALKYL-SUBSTITUTED 4-AMINOPHENYL HALO DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1991-08-07 | — | — | EP | disclosed |
| US-4847295-A | ANTITUMOR AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-07-11 | — | — | US | disclosed |
| EP-0276122-A2 | Cycloalkyl-substituted 4-aminophenyl halo derivatives and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-07-27 | — | — | EP | disclosed |